New Drug Shows Promise for Schizophrenia

Brexpiprazole, a drug currently in trials for the treatment of hyperactivity disorder and depression, has also been shown to be effective and tolerable in schizophrenia patients.

Recent research published in the American Journal of Psychiatry found that brexpiprazole helped schizophrenia patients achieve significant improvements when compared with patients taking a placebo for six weeks.

The trial included 636 patients with acute schzophrenia.

“Schizophrenia is a complicated disease and, while advances have been made, patients often still lack an effective treatment path” said Dr. Christoph U. Correll, lead investigator of the study.

Fewer side effects?

The trial also showed that patients taking brexpiprazole experienced similar levels of treatment-related side effects as those taking a placebo, which included restless insomnia anxiety and sedation.

Additionally, researchers said the drug was not linked to any clinically significant effects on either LDL or HDL cholesterol or triglycerides - an encouraging finding given that many antipsychotic medications have been associated with raised cholesterol levels and higher risk for cardiovascular incidents.

“It is important for clinicians and patients to have a range of treatment options to manage symptoms, and the publication of these data helps increase awareness of the potential of brexpiprazole in this patient population," concluded Dr. Correll.

Source: Pharmiweb, Drugs.com

Image courtesy of amenic181/FreeDigitalPhotos.net

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