Research May Point to New Drug Targets For Schizophrenia

When you're treated with a medication for a disorder like schiozphrenia, the drug works by interacting with receptors that reside in your body’s cells. Receptors bind with molecules such as neurotransmitters and hormones, and respond to those molecules in a way that triggers an effect on its cell. Researchers are always looking for receptors that may be potential targets for new medications, and the authors of a recent study have tested out a new method for uncovering these drug targets.

New receptors identified

While there are already methods in place for finding new receptors on cells, they use techniques that miss uncommon receptors. This newer method, tested by Tamas Bartfai and James Eberwine, used DNA sequencing to identify more than 400 receptors.

The researchers in this study looked at class of nerve cells that regulate body temperature, but their technique can be applied to other types of nerve cells in the brain, such as those involved in schizophrenia. The hope is that this new method will help identify "hidden" receptors that may be good targets for new drugs for schizophrenia, Parkinson's, and other diseases.

Read more about the study, published in the journal Pharmacology and Therapeutics, at http://www.sify.com/news/new-study-could-lead-to-potential-drug-targets-...

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