Schizophrenia and Bipolar Disorder Share Brain Similarities

The first study to look at sub-regions of the brain's hippocampus has revealed striking similarities in the brains of people with bipolar disorder and schizophrenia. Conducted by researchers from the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital, the study is also the first to identify alterations in a process of information transmission from neuron to neuron that occurs in both disorders.

Prior research has consistently found hippocampus abnormalities in people with schizophrenia. This study found that proteins in certain areas of the hippocampus were affected differently in people with schizophrenia than those in the general population, and these differences were found to be nearly identical in people with bipolar disorder. Both disorders also had alterations in the process by which proteins aid in the transmission of information to and from the synapse between neurons.

"Our study is the first to show the depth of protein similarities between schizophrenia and bipolar disorder as they appear in the brain and the processes associated with them. Although, the two conditions present with different symptoms, the research has shown that they are almost identical in terms of how they present in the brain," said Professor David Cotter of RCSI and Beaumont Hospital.

Read more: http://www.medicalnewstoday.com/releases/233371.php

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